Claverie-Benureau S, Lebel B, Gaudin-Harding F
J Physiol (Paris). 1980;76(2):173-5.
Two groups of rats, one hairy and one hairless, received either a magnesium deficient diet (4 mg Mg/100 g diet) or a control diet (40 mg/100 g diet). After four days, an easily observable redness of the skin occurred in the hairless deficient group, progressing from the tail to the forehead, and later a hyperemia of the ear and dermatosis which increased with scratching appeared in both deficient groups. The clinical signs were more acute in the deficient hairless group. Histamine, total white blood cells and eosinophil counts increased in both deficient groups during the allergy-like crisis. Then, these factors tended to normal values. After three weeks on a diet an enlargement of the spleens was observed, but not of the thymus in both deficient groups. There was a large difference in the histamine content of the spleen between the deficient and control hairless groups: the values obtained were 4 350 ng and 166 ng per 100 g tissue respectively.
两组大鼠，一组有毛，一组无毛，分别给予缺镁饮食（4毫克镁/100克饮食）或对照饮食（40毫克/100克饮食）。四天后，无毛缺镁组皮肤出现易于观察到的发红，从尾巴蔓延至前额，随后两个缺镁组均出现耳部充血和因搔抓而加重的皮肤病。缺镁无毛组的临床症状更为严重。在类似过敏的危机期间，两个缺镁组的组胺、白细胞总数和嗜酸性粒细胞计数均增加。然后，这些指标趋于正常。饮食三周后，两个缺镁组均观察到脾脏肿大，但胸腺未肿大。缺镁无毛组与对照无毛组脾脏中的组胺含量存在很大差异：每100克组织中获得的值分别为4350纳克和166纳克。
