García-Bragado F, Gallart M T, Vilardell M, Fonollosa V, Rodrigo M J, Monreal M
Med Clin (Barc). 1980 Jul 15;75(3):129-31.
Cryoglobulins are serum immunoglobulins (immunocomplexes) that precipitate in the cold and redissolve on warming. Cryoglobulins from patients with several diseases showed the presence of antiDNA antibodies when previously underwent incubation in acid buffer. The possibility that antiDNA antibodies might constitute the immunocomplexes found in patients with systemic lupus erythematosus and with other connective tissue diseases is suggested. Negative findings in relation to the presence of antiDNA antibodies in cryoglobulins of a case with sicca syndrome are reported.
冷球蛋白是在低温下沉淀并在升温时重新溶解的血清免疫球蛋白（免疫复合物）。来自患有多种疾病患者的冷球蛋白在先前于酸性缓冲液中孵育时显示出抗DNA抗体的存在。这提示了抗DNA抗体可能构成系统性红斑狼疮和其他结缔组织病患者体内发现的免疫复合物。本文报道了一例干燥综合征患者冷球蛋白中抗DNA抗体检测呈阴性的结果。
