Steiner D, Böcker W
Langenbecks Arch Chir. 1980;351(1):69-76. doi: 10.1007/BF01241932.
The morphology and biology of tumors of the nerve sheath show rather heterogeneous aspects. In most the site of origin seems to be the Schwann's cells. Essentially these tumors can be differentiated into three groups: 1. malignant schwannoma, 2. neurinoma, and 3. neurofibroma. Although the Schwann's cell is the common origin, the three different tumors can be well differentiated histologically with the exception of malignant schwannoma and spindle cell sarcoma. The clinical symptoms are determined by the location of the tumor and are without general characteristics. The treatment of choice is always radical surgery. In addition, radiation and chemotherapy are indicated in special cases.
神经鞘肿瘤的形态学和生物学表现出相当多的异质性。在大多数情况下,肿瘤的起源部位似乎是施万细胞。本质上,这些肿瘤可分为三组:1. 恶性神经鞘瘤;2. 神经瘤;3. 神经纤维瘤。尽管施万细胞是共同起源,但除了恶性神经鞘瘤和梭形细胞肉瘤外,这三种不同的肿瘤在组织学上可以很好地区分。临床症状取决于肿瘤的位置,没有一般特征。首选的治疗方法始终是根治性手术。此外,在特殊情况下需要进行放疗和化疗。