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长春新碱、阿霉素、环磷酰胺和咪唑甲酰胺联合化疗转移性恶性神经鞘瘤：一例报告

Combination chemotherapy of metastatic malignant schwannoma with vincristine, adriamycin, cyclophosphamide, and imidazole carboxamide: a case report.

作者信息

Goldman R L, Jones S E, Heusinkveld R S

出版信息

Cancer. 1977 May;39(5):1955-8. doi: 10.1002/1097-0142(197705)39:5<1955::aid-cncr2820390507>3.0.co;2-f.

DOI:10.1002/1097-0142(197705)39:5<1955::aid-cncr2820390507>3.0.co;2-f
PMID:858125
Abstract

This report describes a patient with a 15-year history of schwannoma (peripheral nerve sheath sarcoma) who developed extensive pulmonary metastases associated with hypoxemia. Treatment with chemotherapy consisting of cyclophosphamide, vincristine, Adriamycin, and imidazole carboxamide resulted in a complete remission lasting 17+ months. Malignant schwannoma should probably be regarded as a drug sensitive neoplasm.

摘要

本报告描述了一名患有神经鞘瘤（周围神经鞘肉瘤）15年的患者，该患者出现了广泛的肺转移并伴有低氧血症。采用环磷酰胺、长春新碱、阿霉素和咪唑甲酰胺组成的化疗方案进行治疗，实现了持续17个多月的完全缓解。恶性神经鞘瘤可能应被视为一种对药物敏感的肿瘤。

相似文献

1
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Excellent response of malignant peripheral nerve sheath tumour of retroperitoneum to radiation therapy.
腹膜后恶性外周神经鞘瘤对放射治疗的良好反应。
BMJ Case Rep. 2012 Dec 17;2012:bcr2012007266. doi: 10.1136/bcr-2012-007266.
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J Neurooncol. 2006 Jun;78(2):173-7. doi: 10.1007/s11060-005-9083-z. Epub 2006 Mar 24.
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Korean J Intern Med. 2005 Mar;20(1):100-4. doi: 10.3904/kjim.2005.20.1.100.
6
[Malignant schwannoma of the trachea].
HNO. 2003 Sep;51(9):733-6. doi: 10.1007/s00106-002-0800-z. Epub 2003 Apr 11.
7
Primary spinal malignant schwannomas: clinical and prognostic remarks.
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