Neyer U, Mähr G, Ell P J, Meixner M, Gloor F
Minerva Med. 1978 Nov 30;69(58):3951-9.
Biochemical tests (serum calcium, inorganic phosphate and alkaline phosphatase), as well as clinical, radiological, scanning and histological investigations were undertaken in 24 patients in chronic renal failure. The frequency with which the diagnosis of renal osteopathy could be made depended in the method of investigation, the biochemical findings proving to be completely unreliable. There were positive radiological signs in ten patients and clinical signs in 12, predominantly in the progressive stages of osteopathy. A positive scan was obtained in 23 patients, typical histological bone changes in an equal number. Since it correlates so well with the histological findings, bone scan is suitable particularly in the early diagnosis of osteopathy. Since this test is easily performed and hardly stresses the patient, it should routinely be the initial one for the diagnosis of renal osteopathy.
对24例慢性肾衰竭患者进行了生化检查(血清钙、无机磷和碱性磷酸酶)以及临床、放射学、扫描和组织学检查。能否诊断为肾性骨病取决于检查方法,生化检查结果被证明是完全不可靠的。10例患者有阳性放射学征象,12例有临床体征,主要出现在骨病的进展期。23例患者扫描呈阳性,同样数量的患者有典型的组织学骨改变。由于骨扫描与组织学检查结果相关性良好,因此特别适用于骨病的早期诊断。由于该检查操作简便且对患者几乎没有负担,故应常规作为肾性骨病诊断的首选检查。