从两名多发性硬化症患者的中枢神经系统组织中分离出两种冠状病毒。

Two coronaviruses isolated from central nervous system tissue of two multiple sclerosis patients.

作者信息

Burks J S, DeVald B L, Jankovsky L D, Gerdes J C

出版信息

Science. 1980 Aug 22;209(4459):933-4. doi: 10.1126/science.7403860.

Abstract

Two coronaviruses were isolated from brain material obtained at autopsy from two multiple sclerosis patients. The viruses were neutralized by serum and spinal fluid from these patients. Although most of the population have antibody to these virus isolates, multiple sclerosis patients have slightly higher concentrations of serum antibody than controls. The results suggest that coronaviruses should be considered as one additional virus with a potential implication in the etiology of multiple sclerosis.

摘要

从两名多发性硬化症患者尸检获得的脑材料中分离出两种冠状病毒。这些病毒被这些患者的血清和脑脊液中和。尽管大多数人群对这些病毒分离株有抗体，但多发性硬化症患者的血清抗体浓度略高于对照组。结果表明，冠状病毒应被视为另一种可能与多发性硬化症病因有关的病毒。