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[实验性横纹肌肉瘤中细胞大小的遗传力]

[Heritability of cell size in experimental rhabdomyosarcomas].

作者信息

Stepan'ian L I, Vakhtin Iu B

出版信息

Tsitologiia. 1980 Jul;22(7):823-33.

PMID:7404662
Abstract

Cell diameter and cell value variations were studied in murine and rat rhabdomyosarcomas, both in clones obtained in lung tissue, and in subcutaneous tumors. Coefficients of heritability (h2) of these characters were calculated on the basis of their variances. They were equal to 0.15--0.31 for the diameters of cells, and 0.13--0.87 for the cell volumes. The problem of investigation of heritability of quantitative characters in somatic cell populations is discussed.

摘要

在小鼠和大鼠横纹肌肉瘤中,对肺组织克隆以及皮下肿瘤中的细胞直径和细胞值变化进行了研究。根据这些特征的方差计算了它们的遗传力系数(h2)。细胞直径的遗传力系数为0.15 - 0.31,细胞体积的遗传力系数为0.13 - 0.87。文中讨论了体细胞群体中数量性状遗传力的研究问题。

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