一个法裔加拿大家庭中的罕见血型En(a-)表型。

The rare phenotype En(a-) in a French-Canadian family.

作者信息

Taliano V, Guévin R M, Hébert D, Daniels G L, Tippett P, Anstee D J, Mawby W J, Tanner M J

出版信息

Vox Sang. 1980 Feb;38(2):87-93. doi: 10.1111/j.1423-0410.1980.tb02335.x.

DOI:10.1111/j.1423-0410.1980.tb02335.x

Abstract

A French-Canadian En(a-) propositus, whose red cells are phenotypically like the three previously reported, differs in the mode of reaction of this antibody which is apparently not immune. His consaguineous parents and 2 of this 4 sibs are heterozygous EnaEn, the other 2 being EnaEna. Sialic acid levels and the MN glycoprotein content of the red cells of the family and the PAS-straned patterns of the red cell membranes of the propositus confirm the serological findings.

摘要

一名法裔加拿大籍的En(a-)先证者，其红细胞表型与之前报道的3例相似，但其体内这种抗体的反应模式有所不同，该抗体显然并非免疫性的。其近亲父母及4个同胞中的2个为EnaEn杂合子，另外2个为EnaEna。该家族成员红细胞的唾液酸水平、MN糖蛋白含量以及先证者红细胞膜的PAS染色模式均证实了血清学检查结果。