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[Calusterone (7-beta, 17-alpha-dimethyltestosterone) in the palliative treatment of advanced breast cancer].

作者信息

Robustelli Della Cuna G, Bernardo G, Strada M R

出版信息

Minerva Med. 1977 Oct 31;68(52):3555-63.

PMID:74052
Abstract

Results in palliative treatment of advanced breast cancer with a new androgen, calusterone, are discussed. Sixty post-menopausal patients with metastatic breast carcinoma were treated with 200 mg per day at least three months. The overall response was 28% (17/60); better results seemed to be achieved in advanced post-menopausal patients with osseous and cutaneous lesions. These results agree with those reported by the Cooperative Breast Cancer Group. No undesirable side-effects were observed and calusterone was well tolerated.

摘要

相似文献

1
[Calusterone (7-beta, 17-alpha-dimethyltestosterone) in the palliative treatment of advanced breast cancer].
Minerva Med. 1977 Oct 31;68(52):3555-63.
2
Antitumor efficacy of 7 beta, 17 alpha-dimethyltestosterone (Calusterone) in advanced female breast cancer.7β,17α-二甲基睾酮(卡鲁睾酮)对晚期女性乳腺癌的抗肿瘤疗效。
Calif Med. 1970 Sep;113(3):1-10.
3
[Clinical considerations on the use of a new synthetic androgen, Calusterone, in the treatment of advanced breast cancer].[关于使用新型合成雄激素卡鲁睾酮治疗晚期乳腺癌的临床考量]
Minerva Med. 1977 Jul 28;68(36):2499-504.
4
Calusterone therapy for advanced breast cancer.卡鲁睾酮治疗晚期乳腺癌。
Cancer Treat Rep. 1977 May-Jun;61(3):371-3.
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Letter: Calusterone (NSC-88536) in advanced breast cancer.信件:卡鲁睾酮(NSC - 88536)用于晚期乳腺癌
Cancer Treat Rep. 1976 Mar;60(3):220-1.
6
Male breast cancer: two cases with objective regressions from calusterone (7 alpha, 17 beta-dimethyltestosterone) after failure of orchiectomy.男性乳腺癌:两例在睾丸切除术失败后使用卡鲁睾酮(7α,17β - 二甲基睾酮)获得客观缓解的病例。
Oncology. 1976;33(4):188-91. doi: 10.1159/000225140.
7
Effect of 7beta, 17alpha-dimethyltestosterone (calusterone) on cortisol metabolism in women with advanced breast cancer.
J Clin Endocrinol Metab. 1976 Jul;43(1):38-45. doi: 10.1210/jcem-43-1-38.
8
Calusterone.卡鲁睾酮
Ann Intern Med. 1978 Dec;89(6):945-8. doi: 10.7326/0003-4819-89-6-945.
9
Leucopoietic effect of calusterone (7 beta, 17 alpha-dimethyltestosterone) in women with advanced breast cancer.卡鲁睾酮(7β,17α-二甲基睾酮)对晚期乳腺癌女性的升白作用。
Scand J Haematol. 1973;10(3):177-80. doi: 10.1111/j.1600-0609.1973.tb00056.x.
10
7beta,17alpha-Dimethyltestosterone (calusterone)-induced changes in the metabolism, production rate, and excretion of estrogens in women with breast cancer: a possible mechanism of action.
J Clin Endocrinol Metab. 1976 Feb;42(2):365-9. doi: 10.1210/jcem-42-2-365.