Davidson J, Turnbull C D, Miller R D
Acta Psychiatr Scand. 1980 May;61(5):377-86. doi: 10.1111/j.1600-0447.1980.tb00876.x.
Retrospective comparisons between primary unipolar depression and depression secondary to anxiety in 65 inpatients revealed a number of differences. Secondary depression was associated with a significantly higher incidence of neurotic traits in childhood, chronic unhappiness, and unsupportive family. Tricyclic antidepressants and ECT were both more effective in primary depression, and some secondary depressives became worse on ECt. When primary depression was sub-divided into familial, nonfamilial and spectrum types, the greatest differences were noted between familial and secondary depressions. In the former group a more stable life style was noted. Secondary and spectrum types differed on only two variables and several similarities were noted. Platelet monoamine oxidase activity was significantly higher in secondary depression.
对65名住院患者的原发性单相抑郁症与继发于焦虑症的抑郁症进行回顾性比较，发现了一些差异。继发性抑郁症与儿童期神经症特质、长期不快乐以及缺乏支持的家庭环境的发生率显著较高有关。三环类抗抑郁药和电休克疗法对原发性抑郁症都更有效，而一些继发性抑郁症患者接受电休克疗法后病情反而加重。当将原发性抑郁症细分为家族性、非家族性和谱系性类型时，家族性抑郁症和继发性抑郁症之间的差异最为明显。在前一组中，观察到更稳定的生活方式。继发性抑郁症和谱系性抑郁症仅在两个变量上存在差异，且发现了一些相似之处。继发性抑郁症患者的血小板单胺氧化酶活性显著更高。
