Angst J, Dobler-Mikola A
Eur Arch Psychiatry Neurol Sci. 1985;235(3):179-86. doi: 10.1007/BF00380990.
A representative sample of 456 persons from the normal population aged 22 and 23 years was used to study the overlap of depression with anxiety disorders. The 1-year prevalence rate for major depression (DSM-III), minor depression, and anxiety disorder together was 16.4%. The observed cases of major depression occurred in 36% with anxiety disorder, the cases with minor depression in 60%. On the level of symptoms assessed by a semistructured clinical interview and on the level of self-assessed items of the symptom check list SCL-90, the overlap was even greater. The main finding was that subjects with both diagnoses, depression and anxiety disorder, were more severely affected in general. Discriminant analyses of the SCL-90 scales together with the qualitative distribution of SCL items characterizing depression, anxiety, or phobia, did not disprove the hypothesis of a continuum.
从22岁和23岁的正常人群中选取了456人的代表性样本，用于研究抑郁症与焦虑症的重叠情况。重度抑郁症（DSM-III）、轻度抑郁症和焦虑症的1年患病率总计为16.4%。观察到的重度抑郁症病例中，36%同时患有焦虑症，轻度抑郁症病例中，60%同时患有焦虑症。在通过半结构化临床访谈评估的症状水平以及症状自评量表SCL-90的自我评估项目水平上，重叠更为明显。主要发现是，同时患有抑郁症和焦虑症这两种诊断的受试者总体上受影响更严重。对SCL-90量表进行判别分析，并结合表征抑郁、焦虑或恐惧症的SCL项目的定性分布，并未否定连续性假设。
