Kohler J P, Simonowitz D, Paloyan D
Am Surg. 1980 Aug;46(8):449-52.
Preoperative and postoperative carcinoembryonic antigen (CEA) levels were evaluated in 42 patients with colorectal carcinoma. Preoperative CEA values correlated inversely with survival at a statistically significant level and provided prognostic information not available by pathologic staging. Postoperative plasma CEA can accurately predict recurrent disease and may, when serial values are elevated, serve as an indication for a second-look procedure.
对42例结肠直肠癌患者的术前和术后癌胚抗原(CEA)水平进行了评估。术前CEA值与生存率呈负相关,具有统计学意义,并提供了病理分期无法获得的预后信息。术后血浆CEA可准确预测疾病复发,当系列值升高时,可作为二次探查手术的指征。