Bennett W M, Muther R S, Parker R A, Feig P, Morrison G, Golper T A, Singer I
Ann Intern Med. 1980 Aug;93(2):286-325. doi: 10.7326/0003-4819-111-3-286.
Data providing guidelines for drug use in adult patients with renal insufficiency are presented in tabular form with supporting references. The data are derived from the current medical literature. If specific information about a drug is unavailable or conflicting, emphasis is given to normal pharmacokinetic variables in arriving at recommendations for therapy. Nephrotoxicity or adverse effects in patients with renal disease are noted and adjustments for dialysis suggested.
以表格形式呈现了为肾功能不全成年患者用药提供指导的数据,并附有参考文献。这些数据源自当前医学文献。如果关于某种药物的具体信息不可得或相互矛盾,在得出治疗建议时会着重考虑正常的药代动力学变量。文中指出了肾病患者的肾毒性或不良反应,并建议了透析调整措施。