肾衰竭的药物治疗：成人用药指南。第一部分：抗菌药物、镇痛药。

Drug therapy in renal failure: dosing guidelines for adults. Part I: Antimicrobial agents, analgesics.

作者信息

Bennett W M, Muther R S, Parker R A, Feig P, Morrison G, Golper T A, Singer I

出版信息

Ann Intern Med. 1980 Jul;93(1):62-89. doi: 10.7326/0003-4819-93-1-62.

Abstract

Data are presented in tabular form that provide guidelines for drug use in adult patients with renal insufficiency. The data are derived from the current medical literature. If specific information about a drug is unavailable or conflicting, emphasis is given to normal pharmacokinetic variables in arriving at recommendations for therapy. Nephrotoxicity or adverse effects in patients with renal disease are noted and adjustments for dialysis suggested.

摘要

数据以表格形式呈现，为肾功能不全成年患者的用药提供指导方针。这些数据源自当前医学文献。如果关于某种药物的具体信息不可用或相互矛盾，在得出治疗建议时会着重考虑正常的药代动力学变量。文中指出了肾病患者的肾毒性或不良反应，并提出了透析调整建议。