聚合物-溶剂组合物对火棉胶膜人工细胞形成的影响。
The effects of polymer-solvent compositions on the formation of collodion membrane artificial cells.
作者信息
Yu Y T, Chang T M
出版信息
Biomater Med Devices Artif Organs. 1980;8(3):273-81. doi: 10.3109/10731198009118984.
This study is an attempt to analyze the various polymer-solvent compositions for preparing collodion membrane artificial cells for biomedical applications. Cellulose nitrate was disolved in different mixtures of alcohol-ether solutions and used for microencapsulation. The most optimal solvent solution consisted of 4 g% cellulose nitrate in 17.5% (volume) alcohol and 82.5% (volume) ether. The urease microcapsules prepared this way showed no leakage of enzyme under test conditions. Having established the optimal polymer-solvent compositions, an easier and more reproducible procedure has been established for preparing collodion membrane artificial cells.
本研究旨在分析用于制备生物医学应用的火棉胶膜人工细胞的各种聚合物 - 溶剂组合物。硝酸纤维素溶解于不同的醇 - 醚溶液混合物中，并用于微囊化。最适宜的溶剂溶液是由4g%硝酸纤维素、17.5%（体积）乙醇和82.5%（体积）乙醚组成。用这种方法制备的脲酶微囊在测试条件下未显示出酶泄漏。在确定了最佳的聚合物 - 溶剂组合物后，已建立了一种更简便且可重复的制备火棉胶膜人工细胞的方法。
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