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[脑静脉压及其与体静脉压和脑水肿发展的关系]

[Venous pressure in the brain, its relationship to systemic venous pressure and to the development of cerebral edema].

作者信息

Mchedlishvili G I, Sikharulidze N V, Itkis M L, Ianushevskiĭ S

出版信息

Biull Eksp Biol Med. 1980 Jul;89(7):14-6.

PMID:7407364
Abstract

Studies on rabbits have shown that cerebral venous pressure (continuosly recorded in the sagittal venous sinus) is linearly dependent on the systemic venous pressure measured from the cranial vena cava. On the other hand, the changes in the brain volume are also linearly dependent on the systemic and hence the cerebral venous pressure. In the preedematous brain, the slope of the curve considerably rose due to the increased pliancy of its tissue. When brain edema developed the slope fo the curve became appreciably less as compared to the normal brain. This is evident of the increased rigidity of edematous brain tissue.

摘要

对兔子的研究表明,脑静脉压(在矢状窦中连续记录)与从颅腔静脉测量的体静脉压呈线性相关。另一方面,脑容量的变化也与体静脉压以及由此产生的脑静脉压呈线性相关。在脑水肿前期,由于脑组织柔韧性增加,曲线斜率显著上升。当发生脑水肿时,与正常脑相比,曲线斜率明显变小。这表明脑水肿组织的硬度增加。

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