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[刺激下丘脑核时大鼠肠系膜和骨骼肌微循环变化与体动脉压的关系]

[Microcirculatory changes in the mesentery and skeletal muscle of the rat in relation to systemic arterial pressure during stimulation of the hypothalamic nuclei].

作者信息

Veĭt V K, Chernukh A M

出版信息

Biull Eksp Biol Med. 1980 Aug;90(8):139-42.

PMID:7407382
Abstract

In acute experiments on anesthetized rats, hypothalamus sites were stimulated through bipolar electrodes. Vasomotor reactions and blood flow in mesenteric and spinotrapezius muscle vessels were studied and recorded by intravital microscopy and microphotography. Systemic blood pressure (BP) was measured in the carotid artery via a catheter. The results indicate that electric stimulation of different hypothalamus sites induces pressor, depressor or biphasic BP reactions that are related to the site stimulated. Microcirculatory changes were monotonous. Regardless of BP reaction in the microcirculatory network of the mesentery, the transient acceleration, slowdown and stoppage of the blood flow were observed in mesenteric microvessels (10--70 micrometer) without changes in their diameter. Pronounced constriction of the diameter of small arteries (90--250 micrometer) were also recorded in the mesentery. During BP pressor reaction the dilatation of microvessels (5--40 micrometer) of the skeletal muscle and an increase in their blood content were noted.

摘要

在对麻醉大鼠进行的急性实验中,通过双极电极刺激下丘脑部位。利用活体显微镜和显微摄影术研究并记录了肠系膜和斜方肌血管的血管运动反应及血流情况。通过导管测量颈动脉的全身血压(BP)。结果表明,对不同下丘脑部位的电刺激会诱发与刺激部位相关的升压、降压或双相血压反应。微循环变化是单调的。无论肠系膜微循环网络中的血压反应如何,在肠系膜微血管(10 - 70微米)中均观察到血流的短暂加速、减慢和停滞,而其直径无变化。在肠系膜中还记录到小动脉(90 - 250微米)直径的明显收缩。在血压升压反应期间,观察到骨骼肌微血管(5 - 40微米)扩张且其血液含量增加。

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[Microcirculatory changes in the mesentery and skeletal muscle of the rat in relation to systemic arterial pressure during stimulation of the hypothalamic nuclei].[刺激下丘脑核时大鼠肠系膜和骨骼肌微循环变化与体动脉压的关系]
Biull Eksp Biol Med. 1980 Aug;90(8):139-42.
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