Aspiz M E, Starosvetskaia N A
Biull Eksp Biol Med. 1980 Aug;90(8):203-5.
The statmokinetic reaction of malignant-transformed cells of a hamster tumor (CHT-1) was induced by colcemid. The reversibility of the reaction is primarily related to the repolymerization of spindle microtubules from the tubuline pool of the precursors. The character of the statmokinetic reaction reversibility in the test cells evidences the activity of polymerization processes in them. The course of these processes in the presence of copper ions did not differ from that in nonmalignant-transformed cells.
秋水仙酰胺可诱导仓鼠肿瘤(CHT-1)恶性转化细胞的静止运动反应。该反应的可逆性主要与纺锤体微管从前体微管蛋白库中重新聚合有关。受试细胞中静止运动反应的可逆性特征证明了其中聚合过程的活性。在铜离子存在的情况下,这些过程的进程与未恶性转化的细胞并无差异。