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[亚适宜温度诱导的生长停滞动力学反应的可逆机制]

[Mechanisms of the reversibility of the stathmokinetic response induced by suboptimal temperature].

作者信息

Boltovskaia M N

出版信息

Biull Eksp Biol Med. 1978 Feb;85(2):205-7.

PMID:564722
Abstract

Autoradiographic research with leucine-3H showed that the reversibility of the statmokinetic reaction induced by the suboptimal temperature (21 degrees C) did not require any additional protein synthesis and therefore was not connected with the neoformation of the microtubules. Normalization of the mitotic rate was delayed in the presence of copper ions preventing polymerization of microtubules. These data suggest that repolymerization of microtubules subunits was the principal way of mitosis recovery after the action of suboptimal temperature.

摘要

用3H-亮氨酸进行的放射自显影研究表明,由次优温度(21摄氏度)诱导的静止运动反应的可逆性不需要任何额外的蛋白质合成,因此与微管的新生无关。在存在防止微管聚合的铜离子的情况下,有丝分裂率的正常化被延迟。这些数据表明,微管亚基的重新聚合是次优温度作用后有丝分裂恢复的主要方式。

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