Glatt M M
Fortschr Med. 1980 May 29;98(20):784-6.
In the case of many alcoholics there is a risk of misuse of, and dependence on, sedative drugs, including clomethiazole. Used strictly in its proper indication and in the proper manner, the risk of dependence on clomethiazole is probably rather small. Proper indication and use in the case of alcoholics means treatment limited in time to the withdrawal period, i.e. as a rule not longer than six to seven days. Non-alcoholic/elderly patients suffering from cerebral sclerosis do not tend to misuse drugs; unlike alcoholics, there is therefore in the case of such elderly patients in general no risk of the development of dependence.
对于许多酗酒者而言,存在滥用和依赖包括氯美噻唑在内的镇静药物的风险。严格按照其适当的适应症和正确的方式使用,对氯美噻唑产生依赖的风险可能相当小。对于酗酒者,适当的适应症和使用意味着治疗时间仅限于戒断期,即通常不超过六至七天。患有脑硬化症的非酗酒/老年患者不易滥用药物;因此,与酗酒者不同,这类老年患者一般不存在产生药物依赖的风险。