Zechner O, Pflüger H
Invest Urol. 1980 Sep;18(2):115-8.
We present a model for oral uric acid loading which may be used to study the relapsing tendency of stone-formers. The oral administration of 2 g of guanosine was associated with two different response patterns of urinary uric acid excretion in patients with urolithiasis. The two groups also had considerably different relapse rates. The relapsing tendency in the group with the comparatively decreased reaction of urate excretion was less pronounced than in the group with enhanced uric acid excretion after oral purine loading.
我们提出了一种口服尿酸负荷模型，可用于研究结石形成者的复发倾向。对尿路结石患者口服2克鸟苷后，尿尿酸排泄出现了两种不同的反应模式。两组的复发率也有显著差异。口服嘌呤负荷后尿酸排泄反应相对降低的组的复发倾向不如尿酸排泄增加的组明显。
