Zacarian S A
J Dermatol Surg Oncol. 1980 Aug;6(8):627-32. doi: 10.1111/j.1524-4725.1980.tb00937.x.
Conventional monitoring of malignant tumors with thermocouple needles is useful, but has disadvantages. Temperatures are recorded all along the shafts of the thermocouple needles and there is a lag of 10 to 15 seconds before precise temperature is recorded at the tip of the needle. This delay may lead the clinician to underfreeze leions. An alternative and more precise monitoring device that measures the flow of electrical current or the cessation of electrical flow (resistance) as an indication of effective cryonecrosis during freezing is described in this paper. This method affords absolute accuracy and at the same time allows monitoring up to five separate focal areas within a lesion instead of a single site as is currently done with thermocouples.
用热电偶针常规监测恶性肿瘤是有用的，但也有缺点。沿着热电偶针的杆身记录温度，在针的尖端记录精确温度之前有10到15秒的延迟。这种延迟可能会导致临床医生对病变冷冻不足。本文介绍了一种替代的、更精确的监测装置，该装置通过测量电流或电流中断（电阻）来指示冷冻过程中的有效冷冻坏死。这种方法具有绝对的准确性，同时允许在一个病变内监测多达五个不同的焦点区域，而不是像目前使用热电偶那样只监测单个部位。
