Effect of voluntary exercise and dietary protein levels on serum lipoprotein distributions and lecithin: cholesterol acyltransferase (LCAT) activity of mice.

The effect of voluntary exercise on serum lipoprotein distributions, lecitin:cholesterol acryltransferase (LCAT) activity and serum electrophoretic patterns of mice fed different levels of dietary protein were investigated. Serum cholesterol of all exercise groups (E) showed a lower value than that of the non-exercise groups (NE). Ratios of cholesteryl ester to serum total cholesterol tended to be higher in the exercise groups than in non-exercise groups. High density lipoprotein(HDL)-cholesterol/serum total cholesterol ratios and HDL-cholesterol/low density lipoprotein(LDL)-cholesterol ratios were increased by voluntary exercise. With regard to low density lipoprotein cholesterol levels, there were significant differences between 20% E and 20% NE groups, 4% NE groups, respectively. It was found that HDL fractions in serum lipoprotein patterns of exercise groups differed from those of non-exercise groups. This seemed to be prominent in low protein diet groups. LCAT acitivity showed decreasing values as dietary protein levels decreased and its activity was raised by voluntary exercise in all groups.