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[食管念珠菌病]

[Esophageal moniliasis].

作者信息

Ramírez Degollado J, Martínez Aguilar A, Peniche Bojórquez J

出版信息

Rev Gastroenterol Mex. 1978 Sep-Dec;43(3):131-5.

PMID:741142
Abstract

Esophageal moniliasis is found rarely. It has been described mainly in chronically ill patients, who receive antibiotics and corticoesteroids. Early diagnosis and treatment betters their prognosis. Nine patients, 5 males and 4 females were studies in Hospital General del Centro Medico Nacional in Mexico City. Their agesranged from 26 to 77 years, with a mean of 49 years. All patients were chronically ill and 7 of them were treated in the intensive care unit. Three had disphagia, 3 retrosternal pain, and 2 gastrointestinal hemorrhage. Eight patients had high W.B.C., 3 irregular filling defects on X ray studies, and on endoscopy, all showed a pseudomembranous white yellowish exudate, underneath it the mucosa was inflamed, irregular and bled scantily. In 5 out of 9 patients biopsy and a smear confirmed the diagnosis. Eight patients treated with nystatin were cured. This disorder must be suspected in patients with disphagia and retrosternal pain; esophagoscopy is the prefered procedure to establish this diagnosis.

摘要

食管念珠菌病较为罕见。主要在接受抗生素和皮质类固醇治疗的慢性病患者中被描述。早期诊断和治疗可改善其预后。在墨西哥城的国家医学中心综合医院对9例患者进行了研究,其中男性5例,女性4例。年龄在26至77岁之间,平均年龄为49岁。所有患者均患有慢性病,其中7例在重症监护病房接受治疗。3例有吞咽困难,3例有胸骨后疼痛,2例有胃肠道出血。8例白细胞计数升高,3例X线检查有不规则充盈缺损,内镜检查时,所有患者均可见假膜性白色淡黄色渗出物,其下黏膜发炎、不规则且有少量出血。9例患者中有5例经活检和涂片确诊。8例接受制霉菌素治疗的患者治愈。对于有吞咽困难和胸骨后疼痛的患者必须怀疑此病;食管镜检查是确立该诊断的首选方法。

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