Hypostatic leg ulceration and Klinefelter's syndrome.

Sixty-one patients with Klinefelter's syndrome, of both normal and low intelligence, have been found to have a significantly higher frequency of hypostatic leg ulceration than a random sample of normal males, a group of male prisoners and a group of mentally subnormal men. The prevalence of varicose veins in these patients is also greater than in normal men and in prisoners but not significantly different from that of the mentally subnormal group.