Havers W, Majewski F, Olbing H, Eickenberg H U
J Urol. 1980 Jul;124(1):108-10. doi: 10.1016/s0022-5347(17)55320-3.
in addition to the well known major signs of growth retardation, microcephaly, mental retardation and typical craniofacial dysmorphism, malformations of the urinary tract were found in 9 of 110 patients with alcohol embryopathy. Of the 110 patients 21 have been examined adequately. An extensive urologic investigation of children with alcohol embryopathy and symptoms suggesting kidney or genitourinary tract disease is essential for early diagnosis and correction of malformations. Awarness of alcohol embryopathy in a child referred for correction of urinary tract anomalies may help to establish the diagnosis and prevent it in further offspring.
除了众所周知的生长发育迟缓、小头畸形、智力障碍和典型的颅面畸形等主要体征外,在110例酒精胚胎病患者中,有9例发现了泌尿系统畸形。110例患者中有21例接受了充分检查。对患有酒精胚胎病且有肾脏或泌尿生殖道疾病症状的儿童进行广泛的泌尿科检查,对于早期诊断和畸形矫正至关重要。对于因泌尿系统异常前来矫正的儿童,意识到酒精胚胎病可能有助于确立诊断,并防止其在未来后代中出现。