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骨骼肌至心肌实验性游离自体移植的初步报告

Preliminary report on experimental free autografts of skeletal muscle to the myocardium.

作者信息

Thompson N

出版信息

Scand J Plast Reconstr Surg. 1978;12(3):189-93. doi: 10.3109/02844317809012994.

DOI:10.3109/02844317809012994
PMID:741210
Abstract

In three greyhounds, free grafts of pronator teres muscle from the foreleg were applied to the left ventricular myocardium, and showed successful gross and microscopic survival of the graft six months later. The free grafts of skeletal muscle were transplanted as complete muscle bellies two weeks after preliminary denervation by median nerve neurectomy, and at the time of suture to the myocardium, the central end of the divided left phrenic nerve was implanted into the graft. The animals were normally active and preserved normal electrocardiograms after grafting. The use of such grafts in clinical cases of generalized myocardial degeneration or major infarct is considered.

摘要

在三只灵缇犬身上,将取自前腿的旋前圆肌游离移植到左心室心肌,六个月后可见移植组织在大体和显微镜下均存活良好。骨骼肌游离移植体在经正中神经切除术进行初步去神经支配两周后,作为完整的肌腹进行移植,在与心肌缝合时,将切断的左膈神经的近端植入移植体。移植后动物活动正常,心电图保持正常。考虑将此类移植应用于广泛性心肌变性或大面积梗死的临床病例。

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