Sola O M, Dillard D H, Ivey T D, Haneda K, Itoh T, Thomas R
Circulation. 1985 Feb;71(2):341-8. doi: 10.1161/01.cir.71.2.341.
In a series of 15 studies in dogs, sternocleidomastoid muscle was used to replace deficits created in left ventricular myocardium and sternohyoid muscle was used to replace portions of right myocardial wall. The five right ventricular autotransplants resulted in a 100% surgical success rate, with animals electively killed between 3 and 55 weeks after surgery. In 10 left ventricular studies excision of areas varying from 12 X 46 mm to 30 X 60 mm and incisions of from 40 mm to 70 mm in length were performed. Left ventricular studies resulted in a 60% surgical success rate, with clinically healthy animals being killed for study between 2 weeks and 50 weeks after surgery. Animals surviving the critical surgical recovery period showed no loss of weight or changes in activity. Gross findings at autopsy confirmed the viability of the skeletal muscle transplants. Borders were well healed and the grafted tissue was pliable. Histologic studies suggest that revascularization of skeletal muscle occurred from the myocardial side, and that there were healthy myocardial and skeletal muscle fibers at the junction, with evidence of regeneration.
在对狗进行的一系列15项研究中，使用胸锁乳突肌来替代左心室心肌中产生的缺损，使用胸骨舌骨肌来替代右心肌壁的部分组织。5例右心室自体移植手术成功率达100%，术后3至55周对动物进行选择性处死。在10项左心室研究中，切除面积从12×46毫米至30×60毫米不等，切口长度从40毫米至70毫米不等。左心室研究的手术成功率为60%，术后2周至50周对临床健康的动物进行处死用于研究。度过关键手术恢复期存活下来的动物体重未减轻，活动也无变化。尸检的大体检查结果证实了骨骼肌移植的存活情况。边界愈合良好，移植组织柔韧。组织学研究表明，骨骼肌的血管再生是从心肌侧发生的，在交界处有健康的心肌和骨骼肌纤维，并有再生迹象。
