[New findings on the effect of azetazolamide (Diamox) on intraocular pressure and acid-base metabolism of the blood following oral administration].

The reduction in intraocular pressure following administration of 500 mg acetazolamide (Diamox) per os is less pronounced (17%) than was observed after intravenous injection (38%). The occurrence of metabolic acidosis resulting from the administration of Diamox is not time-related to the drop in pressure and is clearly les severe following oral application. This lowers the risk of metabolic decompensation.