Cohen M, Meyers A M, Milne F J, Disler P B, van Blerk P J
S Afr Med J. 1978 Oct 14;54(16):662-4.
The nephrotoxic effects of radiographic contrast media (RCM) used for excretory urography and angiography are described in 9 patients. These effects are usually temporary and reversible, but may be permanent. Predisposing factors resulting in renal damage are identified and discussed. These include diabetes, dehydration, myelomatosis, chronic renal failure of many causes and repeated administrations of contrast media with a short period. Suggestions are made in order to reduce the incidence and severity of functional renal impairment after administration of contrast media.
本文描述了9例在排泄性尿路造影和血管造影中使用放射造影剂(RCM)后出现的肾毒性效应。这些效应通常是暂时且可逆的,但也可能是永久性的。文中确定并讨论了导致肾损伤的易感因素。这些因素包括糖尿病、脱水、骨髓瘤、多种病因所致的慢性肾衰竭以及短期内重复使用造影剂。文中还提出了一些建议,以降低使用造影剂后功能性肾功能损害的发生率和严重程度。