通过酶联免疫吸附测定法检测乙酰胆碱受体和抗受体抗体。
Measurement of acetylcholine receptor and anti-receptor antibodies by ELISA.
作者信息
Norcross N L, Griffith I J, Lettieri J A
出版信息
Muscle Nerve. 1980 Jul-Aug;3(4):345-9. doi: 10.1002/mus.880030412.
PMID:7412778
Abstract
Both acetylcholine receptor (AChR) and antibodies capable of binding to the AChR can be measured using the recently developed enzyme-linked immunosorbent assay (ELISA). The assay is very sensitive and reproducible. Because of the relative simplicity of the ELISA in comparison to radioimmunoassay procedures currently used to measure anti-AChR antibodies, the ELISA may prove valuable as a clinical diagnostic tool for the human disease myasthenia gravis.
摘要
使用最近开发的酶联免疫吸附测定法（ELISA）可以检测乙酰胆碱受体（AChR）和能够与AChR结合的抗体。该测定法非常灵敏且可重复。由于与目前用于检测抗AChR抗体的放射免疫测定法相比，ELISA相对简单，因此ELISA可能被证明是一种用于人类疾病重症肌无力的有价值的临床诊断工具。
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