Bonnaud-Toulze E N, Raine C S
Neuropathol Appl Neurobiol. 1980 Jul-Aug;6(4):279-90. doi: 10.1111/j.1365-2990.1980.tb00212.x.
Morphologic analysis of longitudinal sections of lumbar anterior root tissue from rabbits at different stages of chronic experimental allergic encephalomyelitis has revealed new information on Schwann cell behaviour during early remyelination. Some short remyelinated internodes were displaced laterally towards nodes as other internodes elongated in a stepise fashion to occupy the vacated axonal segments. This suggests that a Schwann cell possesses the ability to remodel its myelin sheath after the initial establishment of the internode. Subaxolemmal densification was found to be formed wherever pairs of Schwann cells overlapped and gap junctions were observed between young Schwann cells.
对处于慢性实验性变应性脑脊髓炎不同阶段的家兔腰前根组织纵切片进行形态学分析,揭示了早期髓鞘再生过程中施万细胞行为的新信息。一些短的再生髓鞘节段向郎飞结侧向移位,而其他节段则呈阶梯状延长,以占据空出的轴突段。这表明施万细胞在节段最初形成后具有重塑其髓鞘的能力。发现在成对施万细胞重叠的任何部位均形成轴膜下致密化,并且在年轻施万细胞之间观察到缝隙连接。