Monakhov K, Perris C
Neuropsychobiology. 1980;6(5):268-79. doi: 10.1159/000117769.
Some evidence has been presented in previous articles supporting the hypothesis that relevant relationships may occur between clinical symptoms of depression and complex EEG features investigated by means of a systemic structural analysis (SSA). The present paper deals with a closer analysis of the clinical-neurophysiological relationships in depressive syndromes. 22 untreated depressed patients of both sexes participated in the study. The patients were rated by means of the Cronholm and Ottosson Rating Scale for Depression (CORSD) at the time of the EEG investigation. Special computer programs were used to investigate the relationships between clinical symptoms and elementary EEG characteristics. It was found that symptoms comprised in the 'anxiety-depression' subscale of the CORSD were related to fast activity in the EEG, whereas symptoms comprised in the 'retardation' subscale showed significant relationship with slow EEG activity. The implicaions of these findings are discussed in terms of excitatory and inhibitory processes in the CNS. Both these processes exhibit a high degree of structural complexity and integration.
在之前的文章中已经提出了一些证据，支持抑郁症临床症状与通过系统结构分析（SSA）研究的复杂脑电图特征之间可能存在相关关系的假设。本文对抑郁综合征中的临床神经生理关系进行了更深入的分析。22名未接受治疗的男女抑郁症患者参与了该研究。在进行脑电图检查时，使用克伦霍尔姆和奥托松抑郁评定量表（CORSD）对患者进行评分。使用特殊的计算机程序来研究临床症状与脑电图基本特征之间的关系。结果发现，CORSD“焦虑-抑郁”子量表中的症状与脑电图中的快速活动有关，而“迟缓”子量表中的症状与脑电图慢活动有显著关系。从中枢神经系统的兴奋和抑制过程方面对这些发现的意义进行了讨论。这两个过程都表现出高度的结构复杂性和整合性。
