Pang P K, Janssen H F, Yee J A
Pharmacology. 1980;21(3):213-22. doi: 10.1159/000137435.
Blood flow rates and vascular resistance in dogs were determined in 14 tissues with 15 +/- 2 microns radioactive microspheres (141Ce, 51Cr, 85Sr). Intravenous injections of synthetic bovine parathyroid hormone containing the NH2-terminal 1--34 amino acids [bPTH-(1--34)] at the dose of 10 USP units/kg body weight produced hypotension and increases in blood flow rate and decreases in resistance in kidney cortex, kidney medulla, heart, liver, stomach and pancreas at 1/2 and 2 min after injection. 4 U bPTH-(1--34)/kg body weight produced less vasodilation. Saline injection had no effect on the tissues studied.
用15±2微米的放射性微球体（141铈、51铬、85锶）测定了犬14种组织的血流速率和血管阻力。静脉注射剂量为10美国药典单位/千克体重的含氨基末端1-34个氨基酸的合成牛甲状旁腺激素[bPTH-(1-34)]后，在注射后1/2分钟和2分钟时，出现低血压，肾皮质、肾髓质、心脏、肝脏、胃和胰腺的血流速率增加，阻力降低。4单位bPTH-(1-34)/千克体重产生的血管舒张作用较小。注射生理盐水对所研究的组织没有影响。
