Haroun E M, Hammond J A, Sewell M M
Res Vet Sci. 1980 May;28(3):377-9.
Whereas one mature or two immature infections with Fasciola hepatica, which had been eliminated by anthelmintic treatment, conferred resistance to reinfection in rats, this did not occur with rabbits. The differences between the hosts were shown by the numbers of flukes which developed following challenge ands by the changes in peripheral eosinophil counts and serum glutamic dehydrogenase levels. In contrast, rabbits gave a stronger serological response (ELISA) than rats but this was not affected by treatment or challenge in either host.
虽然用驱虫药治疗消除了大鼠体内的一次成熟或两次未成熟肝片吸虫感染后，大鼠对再次感染产生了抵抗力，但兔子却没有这种情况。宿主之间的差异通过攻击后发育的吸虫数量以及外周嗜酸性粒细胞计数和血清谷氨酸脱氢酶水平的变化得以体现。相比之下，兔子的血清学反应（ELISA）比大鼠更强，但在任一宿主中，这种反应都不受治疗或攻击的影响。
