Enzyme assay for detecting resistance to reinfection with the liver fluke Fasciola hepatica in rats.

The kinetics of the release of a liver enzyme, glutamate dehydrogenase, into the serum of Fasciola hepatica infected rats was studied. The results support previous work that has shown that barriers to reinfection with this parasite are met before any pronounced liver damage takes place. The presence of this enzyme in serum can be used as an indicator of resistance to reinfection.