Rozenman D, Kessler I, Lancet M
Surg Gynecol Obstet. 1980 Oct;151(4):497-9.
Labor was induced in 64 women in the third trimester, after antepartum fetal death. In 26 patients, hypertonic saline solution was instilled into the uterus; in 24, surgical rupture of the membranes, followed by oxytocin, was tried, and in 14, induction was by amniotomy only. A definite advantage of the last two methods was shown, the mean induction delivery interval being 22.55, 8.96 and 7.20 hours, respectively. Considering also the possible dangers of hypertonic saline solution, the simple method of amniotomy is preferred.
64例妊娠晚期妇女在产前胎儿死亡后引产。26例患者向子宫内注入高渗盐水；24例尝试手术破膜，随后使用缩宫素；14例仅通过人工破膜引产。结果显示后两种方法具有明显优势，平均引产至分娩间隔分别为22.55小时、8.96小时和7.20小时。考虑到高渗盐水可能存在的危险，人工破膜这种简单方法更受青睐。
