Rochat J, Demenge P, Rerat J C
Toxicol Eur Res. 1978 Jan;1(1):23-6.
The use of the rhodamine B as fluorescent tracer in hydrology ask the question of its possible toxic effects in the environment. This study aspire to specify and to complete the results of the former works by the successive examinations of the activity of the rhodamine B in regard to the "daphnies test", its DL50 on the rat and on the mouse, and its cutaneous tolerance. The obtained results confirm the former remarks and express that the solutions of the rhodamine B show any more immediate risks as soon as they appear no more coloured (higher dilutions 1.10(-7)). However it remains to evaluate its long-term carcenogenic activity.
在水文学中使用罗丹明B作为荧光示踪剂引发了其在环境中可能产生的毒性影响问题。本研究旨在通过对罗丹明B在“水蚤试验”中的活性、对大鼠和小鼠的半数致死剂量（LD50）及其皮肤耐受性进行连续检测，来明确并完善先前研究的结果。所获结果证实了先前的观点，并表明一旦罗丹明B溶液不再显色（更高稀释度为1.10(-7)），就不再显示出直接风险。然而，仍有待评估其长期致癌活性。
