Leskovar P, Hartung R, Siebert A, Wellnhofer E
Urologe A. 1980 Jul;19(4):207-13.
Over a period of 4--6 weeks the urinary concentrations of (total calcium, ionized calcium, creatinine and osmolarity in recurrent stone-formers and healthy controls were measured in morning, midday and evening urine samples. The mean urinary concentrations of the (total) calcium were in both groups the same. However, 31% of the stone-formers and only 18% of the controls showed a mean calcium concentration > 5 mmol/l. The ionized calcium, on the contrary, was significantly higher in the stone-formers than in the controls. The lower urinary osmolarity of the recurrent stone-formers led to significantly higher Ca/osmolarity and Ca2+/osmolarity ratios; analogously, the quotient Ca2+/creatinine was also significantly raised in stone-formers.
在4至6周的时间里,对复发性结石形成者和健康对照者晨尿、中午尿和晚尿样本中的(总钙、离子钙、肌酐和渗透压)尿液浓度进行了测量。两组的(总)钙平均尿液浓度相同。然而,31%的结石形成者和仅18%的对照者的平均钙浓度>5 mmol/l。相反,结石形成者的离子钙明显高于对照者。复发性结石形成者较低的尿液渗透压导致钙/渗透压和钙离子/渗透压比值显著升高;类似地,结石形成者的钙离子/肌酐商也显著升高。