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Frequency and morphology of malignant tumours of the thyroid before and after the introduction of iodine-prophylaxis.

作者信息

Hofstädter F

出版信息

Virchows Arch A Pathol Anat Histol. 1980;385(3):263-70. doi: 10.1007/BF00432536.

DOI:10.1007/BF00432536
PMID:7414939
Abstract

Reclassification of malignant goitres surgically removed between 1952-1975 reveals remarkable epidemiological alterations. There is a proportional decrease in undifferentiated carcinoma, which in males also represents an absolute decrease. The decrease is due to a change in maximum incidence from the 5th to the 7th decade. Differentiated carcinomas, especially the papillary tumours, increase. Comparison with findings in Switzerland shows many conformities. Iodine-prophylaxis apparently influences the morphology of thyroid carcinoma, as indicated by the time lag between the introduction of iodine-prophylaxis and the appearance of alterations in incidence. Iodine-prophylaxis, acting in this way, will improve survival rates in thyroid cancer.

摘要

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