Hofstädter F, Ladurner D, Leitner G
Dtsch Med Wochenschr. 1980 Feb 29;105(9):296-302. doi: 10.1055/s-2008-1070653.
Between 1952 and 1977 there has been a considerable change in the type of goitre operated on in the endemic area of the Austrian Tyrol. Iodine prophylaxis had proved significantly more effective in men: the consequences appear earlier and extend into the middle age groups. As a result, the type of surgical specimen is much more like that seen in non-endemic areas. The incidence of diffuse colloid goitre decreased, as that of adenomatous goitre increased. Among the adenomas, the number of the colloid-rich form has increased. Instead of diffuse or multinodular goitre one now frequently encounters the symptom-free, often uninodular, goitre. The total number of goitre operations has also decreased.
1952年至1977年间，奥地利蒂罗尔州地方性甲状腺肿流行地区接受手术治疗的甲状腺肿类型发生了显著变化。碘预防措施在男性中被证明效果显著更佳：其效果出现得更早，并延伸至中年人群体。因此，手术标本的类型更类似于非流行地区所见的类型。弥漫性胶样甲状腺肿的发病率下降，而腺瘤性甲状腺肿的发病率上升。在腺瘤中，富含胶体的类型数量增加。现在，人们经常遇到的是无症状的、通常为单结节的甲状腺肿，而非弥漫性或多结节性甲状腺肿。甲状腺肿手术的总数也有所下降。
