Felgner P
Tropenmed Parasitol. 1978 Dec;29(4):417-22.
Antibody activity in sera of 43 cases with cystic and 5 cases with alveolar echinococcosis was determined against hydatid fluid and extract of E. alveolaris. The results with Stick-ELISA were compared to those obtained with complement fixation and indirect hemagglutination. Results in ELISA were determined in stepless fashion and expressed as multiple of normal activity (MONA). Sensitivities of the different tests with reference to their respective ranges of nonrelevant activities were 95% in ELISA, 95% in indirect hemagglutination and 90% in complement fixation as determined with sera from cystic echinococcosis cases and their homologous antigen. Employing homologous and heterologous antigens, none of the three immunotests allowed the species specific diagnosis of cystic echinococcosis cases, whereas most cases of alveolar echinococcosis could be recognized by their predominant homologous antibody activity in ELISA and complement fixation.
测定了43例囊型包虫病患者和5例肺泡型包虫病患者血清针对棘球蚴液和肺泡棘球绦虫提取物的抗体活性。将斑点酶联免疫吸附测定（Stick-ELISA）的结果与补体结合试验和间接血凝试验的结果进行了比较。酶联免疫吸附测定的结果以无级方式确定，并表示为正常活性倍数（MONA）。以囊型包虫病患者血清及其同源抗原测定，不同试验在各自无关活性范围内的敏感性分别为：酶联免疫吸附测定95%，间接血凝试验95%，补体结合试验90%。使用同源和异源抗原时，三种免疫试验均无法对囊型包虫病病例进行种特异性诊断，而大多数肺泡型包虫病病例可通过酶联免疫吸附测定和补体结合试验中主要的同源抗体活性得以识别。
