Inshakov L N, Molbaev M S
Vopr Onkol. 1980;26(8):62-5.
One hundred and thirty six patients with chronic lesions of the esophagus and stomach were observed dynamically for a 5-year period (with the use of fibroesophagogastroscopy). Twelve patients showed the esophageal cancer development: in 7 of 86 patients with chronic esophagitis and in 5 of 15 patients with leukoplakia. A high incidence of leukoplakia transition into cancer allows its being referrred to an obligate precancer of the esophagus. Atrophic esophagitis presents the background against which leukoplakia arises.
对136例食管和胃部慢性病变患者进行了为期5年的动态观察(采用纤维食管胃镜检查)。12例患者发生了食管癌:86例慢性食管炎患者中有7例,15例白斑患者中有5例。白斑转变为癌症的高发生率使其被视为食管癌的必然癌前病变。萎缩性食管炎是白斑产生的背景。