[Specific erythrocyte adherence reaction: an index of the malignant potentials of noninvasive tumors of the human urothelium].

Histological sections of 30 primary transitional cell tumors (15 papillomas, 2 cancers of the first, 3--the second and 10--the third stage) were employed for the reaction of specific adherenci of erythrocytes to defect ABO(H)-agtigens. The latter were absent in invasive cancers of grade III as well as in the noninvasive eptiheliomas which were associated with invasive recurrences during 2 years. To a considerable or full extent the antigens remained in tumors following the removal of which invasive recurrences beveloped accordingly in 3 years or later. It is suggeested that changing (loss) of ABO(H)-antigenic differentiation in urothelial tumors precedes the onset of invasion at least by 2--3 years.