Kropp K A, Shapiro R S, Jhunjhunwala J S
Urology. 1978 Dec;12(6):631-4. doi: 10.1016/0090-4295(78)90421-1.
The role of renal biopsy in 46 patients with end stage renal failure was assessed. Renal tissue was obtained by open renal biopsy in 24 patients, by needle biopsy in 5, and at bilateral nephrectomy in 17. In 4 patients the renal biopsy specimens showed advanced changes that could only be diagnosed as "end stage kidney". In 42 patients (91 per cent), a precise renal diagnosis was made. In 20 patients (43 per cent) the prebiopsy clinical impression differed from the histologic diagnosis. In the 29 patients undergoing renal biopsy, minor postoperative morbidity occurred in 5. We conclude that a renal biopsy in patients with end stage renal failure will result in a change in clinical diagnosis in a significant number of patients and can be performed with low morbidity.
评估了肾活检在46例终末期肾衰竭患者中的作用。24例患者通过开放性肾活检获取肾组织，5例通过针吸活检获取，17例在双侧肾切除时获取。4例患者的肾活检标本显示有晚期病变，只能诊断为“终末期肾”。42例患者（91%）得到了确切的肾脏诊断。20例患者（43%）活检前的临床印象与组织学诊断不同。在接受肾活检的29例患者中，5例出现了轻微的术后并发症。我们得出结论，终末期肾衰竭患者进行肾活检会使相当一部分患者的临床诊断发生改变，且并发症发生率较低。
