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小鼠旋毛虫和刚地弓形虫的混合感染

Concurrent infections of Trichinella spiralis and Toxoplasma gondii in mice.

作者信息

Yusuf J N, Piekarski G, Pelster B

出版信息

Z Parasitenkd. 1980;62(3):231-40. doi: 10.1007/BF00926564.

DOI:10.1007/BF00926564
PMID:7415416
Abstract

Concurrent infections with two parasites: a nematode, Trichinella spiralis, and a protozoon. Toxoplasma gondii, were investigated. Antibody production (total immunoglobulin and IgM) was similar in double and single infections. However, the number of Toxoplasma cysts in the brains of mice infected with Trichinella and challenged 1-6 weeks later with Toxoplasma was higher than in mice infected with Toxoplasma alone, while mice infected with Toxoplasma and challenged 4-14 days later with Trichinella had lower worm burdens in the intestine than animals infected with Trichinella alone. Greater loss in body weight was observed in mice infected with both parasites than in those infected with either parasite alone.

摘要

对两种寄生虫——一种线虫旋毛虫和一种原生动物刚地弓形虫的合并感染进行了研究。双重感染和单一感染中的抗体产生(总免疫球蛋白和IgM)相似。然而,先感染旋毛虫并在1 - 6周后用弓形虫攻击的小鼠大脑中弓形虫囊肿的数量高于仅感染弓形虫的小鼠,而先感染弓形虫并在4 - 14天后用旋毛虫攻击的小鼠肠道中的虫负荷低于仅感染旋毛虫的动物。与仅感染任一种寄生虫的小鼠相比,同时感染两种寄生虫的小鼠体重减轻更明显。

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本文引用的文献

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The promoting effect of trichinosis on encephalomyocarditis (EMC) virus infection in rats.旋毛虫病对大鼠脑心肌炎(EMC)病毒感染的促进作用。
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Modification of subclinical toxoplasmosis in mice by cortisone, 6-mercaptopurine and splenectomy.可的松、6-巯基嘌呤和脾切除术对小鼠亚临床弓形虫病的影响
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Trichinella spiralis: inhibition of sheep hemagglutinins in mice.旋毛虫:对小鼠绵羊血细胞凝集素的抑制作用
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Immunodepression associated with concomitant toxoplasma and malarial infections in mice.小鼠中与弓形虫和疟疾同时感染相关的免疫抑制。
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[Serological diagnosis of toxoplasmosis using antigens produced in tissue culture].[利用组织培养产生的抗原进行弓形虫病的血清学诊断]
Bull World Health Organ. 1968;39(3):367-74.
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Immunodepression in mice infected with Toxoplasma gondii.感染刚地弓形虫的小鼠的免疫抑制
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Effect of Toxoplasma gondii on the thymus.弓形虫对胸腺的影响。
Nature. 1973 Aug 3;244(5414):301-3. doi: 10.1038/244301a0.
10
Synergistic interaction of two agents in mice: Japanese B encephalitis virus and Trichinella spiralis.两种病原体在小鼠中的协同相互作用:日本乙型脑炎病毒和旋毛虫。
Am J Trop Med Hyg. 1974 Mar;23(2):235-41. doi: 10.4269/ajtmh.1974.23.235.