Pedersen L M, Nielsen G D, Cohr K H
Z Rechtsmed. 1980;85(3):199-203. doi: 10.1007/BF02116320.
A 39-year-old man, accused of driving a car under the influence of ethanol, claimed that the use of an oxitol-containing floor lacquer prior to the drive might have enhanced the concentration of ethanol. Since oxitol has a higher affinity to alcohol dehydrogenase than ethanol, interaction could not be excluded primarily. With the client's informed consent 104 g of ethanol was given orally in a chamber at exposure to 0 ppm and 316 ppm oxitol, respectively. No difference in the elimination rate of ethanol was found. After combined exposure to oxitol and ethanol a decrease of the neutrophilocytes and the thrombocytes was found, as well as an increase of the serum creatine kinase. After exposure solely to ethanol, there were no abnormal blood sample changes.
一名39岁男子被控在乙醇影响下驾车，他声称在驾车前使用了含木糖醇的地板漆可能提高了乙醇浓度。由于木糖醇对乙醇脱氢酶的亲和力高于乙醇，因此不能排除两者之间主要存在相互作用。在获得客户知情同意后，分别在暴露于0 ppm和316 ppm木糖醇的舱室内口服给予104克乙醇。未发现乙醇消除率有差异。木糖醇和乙醇联合暴露后，发现中性粒细胞和血小板减少，同时血清肌酸激酶升高。仅暴露于乙醇后，血液样本未出现异常变化。
