Goedbloed J F
Acta Anat (Basel). 1980;106(1):108-28.
The embryonic growth curves of 38 individual organs and tissues in the mouse and 19 in the rat are given. A method is presented for the estimation of the confidence interval of the time points of the breaks in the growth curves. In some instances, breaks in the organ curves in the mouse coincided with those noted for the whole embryo, at 10.7, 14.5 and 18.1 days, but they also occurred at other times, i.e., 9.4, 12.1, 13.3, and 16.9 days; we call these times 'phase transitions'. The relations between cell multiplication and other factors influencing volume increase are discussed, and also the relation between cell multiplication and changes in shape. Some implications of our work on growth for development in general are put forward.
给出了小鼠38个个体器官和组织以及大鼠19个个体器官和组织的胚胎生长曲线。提出了一种估计生长曲线中断时间点置信区间的方法。在某些情况下，小鼠器官曲线的中断与整个胚胎在10.7、14.5和18.1天出现的中断相吻合，但也在其他时间出现，即9.4、12.1、13.3和16.9天；我们将这些时间称为“阶段转变”。讨论了细胞增殖与影响体积增加的其他因素之间的关系，以及细胞增殖与形状变化之间的关系。提出了我们关于生长的研究工作对一般发育的一些启示。
