Clements R S, Darnell B
Am J Clin Nutr. 1980 Sep;33(9):1954-67. doi: 10.1093/ajcn/33.9.1954.
Since virtually no information is available concerning the myo-inositol content of dietary constituents, we have measured the amount of this material present in 487 foods by gas-liquid chromatography. We observed that the greatest amounts of myo-inositol were present in fruits, beans, grains, and nuts. Fresh vegetables and fruits were found to contain more myo-inositol than did frozen, canned, or salt-free products. The data provided in this report were used to develop diets that contained varying, but known amounts of myo-inositol. The myo-inositol intake that could be provided by such diets ranged from 225 to 1500 mg/day per 1800 kcal and within this range the agreement between the calculated and measured amounts of this material was excellent (r = 0.98). Since abnormalities in the metabolism of myo-inositol have been speculated to play a role in the pathogenesis of the polyneuropathies associated with diabetes mellitus and chronic renal failure, it is possible that the natural history of these neuropahties can be altered by modifying the amount of dietary myo-inositol that is ingested by patients with these diseases.
由于几乎没有关于膳食成分中肌醇含量的信息，我们通过气液色谱法测量了487种食物中这种物质的含量。我们观察到，水果、豆类、谷物和坚果中肌醇含量最高。发现新鲜蔬菜和水果比冷冻、罐装或无盐产品含有更多的肌醇。本报告提供的数据用于制定含有不同但已知量肌醇的饮食。这种饮食所能提供的肌醇摄入量为每1800千卡225至1500毫克/天，在此范围内，这种物质的计算量与测量量之间的一致性非常好（r = 0.98）。由于推测肌醇代谢异常在与糖尿病和慢性肾衰竭相关的多发性神经病的发病机制中起作用，因此通过改变这些疾病患者摄入的膳食肌醇量，有可能改变这些神经病的自然病程。
