Eriksson E, Mobacken H
Acta Derm Venereol. 1977;57(1):45-9.
The effects of local application of crystal violet on the microcirculatory system are reported. The testing system consisted of vital microscopy of the cheek pouch of the hamster and microangiography of rabbit's ear. It appeared that the early microcirculatory disturbances caused by a dilute aqueous solution of crystal violet were transient, whereas considerable tissue toxicity was shown in the long-term experimental model. A direct cytotoxic effect is suggested.
报告了局部应用结晶紫对微循环系统的影响。测试系统包括仓鼠颊囊的活体显微镜检查和兔耳的微血管造影。结果显示,结晶紫稀水溶液引起的早期微循环紊乱是短暂的,而在长期实验模型中显示出相当大的组织毒性。提示有直接的细胞毒性作用。